Dermatology

Medicine of the skin, hair, nails, and mucous membranes — spanning medical, surgical, and aesthetic care.

Foundations

Skin Anatomy

The skin is a layered organ built for barrier defense, sensation, thermoregulation, and immune surveillance.

1) Epidermis

  • Outermost layer; barrier function & melanin production
  • Cells: keratinocytes, melanocytes, Langerhans cells

2) Dermis

  • Collagen, elastin, vessels, nerves, sweat & sebaceous glands
  • Provides elasticity, sensation, and thermoregulation

3) Hypodermis (Subcutis)

  • Adipose layer for insulation and shock absorption
Overview

What Dermatology Covers

Dermatology is the branch of medicine dealing with the skin, hair, nails, and mucous membranes, encompassing both medical and surgical aspects. From the Greek derma (skin) + logia (study), the field addresses >3,000 conditions ranging from cosmetic concerns to life-threatening disease. Given the visibility of skin pathology, dermatology bridges patient-facing clinical care and investigative research.

Training

Dermatologist Training Pathway

StageTypical DurationNotes
Medical School4 yearsMD or DO
Internship1 yearUsually Internal Medicine or General Surgery
Residency3+ yearsMedical, surgical & cosmetic dermatology
Fellowship (optional)1–2 yearsPeds Derm, Dermatopathology, Mohs, Cosmetics

Subspecialties: Pediatric • Dermatopathology • Mohs Surgery • Cosmetic

Prevention

Public Health & Prevention

  • Skin cancer screening and early detection programs
  • Education on sun protection and self-examinations
  • Closing gaps in access and outcomes across skin tones & communities
Clinical Map

Common Dermatologic Conditions

Inflammatory

  • Eczema (Atopic Dermatitis): Chronic pruritus; atopy association
  • Psoriasis: Immune-mediated; erythematous plaques with silvery scale
  • Acne Vulgaris: Pilosebaceous disorder; often hormone-modulated

Infectious

  • Bacterial: Impetigo, cellulitis
  • Fungal: Tinea corporis, candidiasis
  • Viral: Herpes simplex, VZV, molluscum

Neoplastic & Pigmentary

  • Benign: Seborrheic keratoses, nevi
  • Malignant: BCC, SCC, melanoma
  • Vitiligo: Autoimmune melanocyte loss
  • Melasma: UV & hormone-related hyperpigmentation
Beyond the Skin

Dermatology & Systemic Disease

  • Lupus erythematosus: Malar “butterfly” rash may precede systemic involvement
  • Diabetes mellitus: Acanthosis nigricans, necrobiosis lipoidica
  • Paraneoplastic syndromes: Cutaneous clues to occult malignancy
Diagnostics

Diagnostic Techniques

Bedside & Imaging

  • Clinical exam & pattern recognition
  • Dermoscopy
  • Wood’s lamp for pigment & some fungal disorders

Laboratory & Procedures

  • Skin biopsy: punch, shave, excisional
  • Patch testing for contact dermatitis
  • Targeted blood tests: ANA, IgE, autoantibodies

Pattern + Proof

  • History + distribution matter as much as morphology
  • When in doubt: biopsy early (especially for “weird” rashes)
Treatment

Treatment Modalities

Topical

  • Corticosteroids • Retinoids • Antibiotics/Antifungals
  • Calcineurin inhibitors

Systemic

  • Immunosuppressants (e.g., methotrexate, cyclosporine)
  • Biologics (e.g., adalimumab, ustekinumab)
  • Oral antibiotics & antifungals

Procedural & Light

  • Cryotherapy • Electrosurgery • Laser therapy
  • Excisional surgery • Mohs micrographic surgery
  • Narrowband UVB • PUVA (psoralen + UVA)
Practical

Skin Types & Sun Safety

Fitzpatrick Skin Phototypes (I–VI)

  • I–II: Burns easily, minimal tan → higher UV sensitivity
  • III–IV: Sometimes burns, tans uniformly
  • V–VI: Rarely burns, deeply pigmented → melanoma can be acral/mucosal; look beyond sun-exposed sites

Sun Protection

  • Broad-spectrum SPF 30+ daily; SPF 50+ for prolonged outdoor exposure
  • Reapply every 2 hours; UPF clothing; shade 10am–4pm
  • Vitamin D: consider dietary/supplement sources as needed

Reality Check

  • “Cloudy” doesn’t mean “no UV”
  • Neck, ears, hands: the usual SPF graveyard
Equity

Skin of Color Considerations

  • Inflammation may present with purple/gray/ash tones rather than bright erythema
  • Post-inflammatory hyper/hypopigmentation is common; treat inflammation gently to minimize dyspigmentation
  • Acral lentiginous melanoma: carefully examine palms/soles/nail beds
  • Keloid risk higher — favor silicone gel/sheets & pressure therapy in scar care
Red Flags

Melanoma Recognition

ABCDE

  • Asymmetry
  • Border irregular
  • Color variegation
  • Diameter > 6 mm (or evolving smaller)
  • Evolving size/shape/color/symptoms

Ugly Duckling & Red Flags

  • Lesion unlike the patient’s other moles
  • New spot in adulthood; bleeding, non-healing, rapid change

High-Risk Areas

  • Palms/soles
  • Under nails
  • Mucosal sites
Clinical Ladder

Acne Treatment Ladder (Simplified)

  • Mild: topical benzoyl peroxide ± retinoid
  • Moderate: add topical antibiotic (clindamycin) or oral doxycycline
  • Female patients: consider combined OCP or spironolactone for hormonal pattern
  • Severe/nodulocystic or scarring: oral isotretinoin with monitoring

Always use non-comedogenic skincare; emphasize adherence and sun safety with retinoids.

Atopic Dermatitis

Atopic Dermatitis – Step-Up Care

  • Baseline: emollients, trigger avoidance, short lukewarm baths, gentle cleansers
  • Flares: topical steroids by potency/area; calcineurin inhibitors for sensitive sites
  • Refractory/moderate-severe: phototherapy or systemic/biologic therapy per guidelines
  • Antihistamines for itch-related sleep issues (symptomatic); treat superinfection promptly
Psoriasis

Psoriasis – Assess & Treat

  • Severity metrics: BSA, PASI, DLQI for impact
  • Comorbidities: arthritis, metabolic syndrome, depression, cardiovascular risk
  • Mild: topicals (steroids, vitamin D analogs)
  • Moderate–Severe: phototherapy, systemics, or biologics (TNF-α, IL-17/23)
Emergencies

Drug Eruptions & Emergencies

Common Eruptions

  • Morbilliform exanthem (often antibiotics)
  • Urticaria/angioedema
  • Fixed drug eruption (recurrent same site)

SJS/TEN Red Flags

  • Facial edema, mucosal erosions (ocular/oral/genital)
  • Targetoid lesions, skin pain, rapid progression
  • Systemic symptoms (fever, malaise); urgent referral/hospitalization

Do Not “Wait and See”

  • Skin pain + mucosa = move fast
  • Rapid spread = ER-level urgency
Barrier

Skin Microbiome & Barrier

  • Barrier repair (ceramides, occlusives) reduces TEWL and flares
  • Over-sanitization can disrupt commensals; balance cleansing with barrier support
  • Diet, stress, and sleep influence inflammation and skin health
Basics

Wound & Scar Care Basics

  • Clean, moist wound environment promotes re-epithelialization
  • Petrolatum for simple wounds; avoid peroxide/iodine on fresh tissue
  • Scar modulation: silicone gel/sheets, massage, sun protection; consider laser or injections for hypertrophic/keloid
Telehealth

Teledermatology – Photo Tips

  • Good indirect daylight; neutral background; no flash glare
  • Include a ruler/coin for scale; take overview + close-ups
  • Capture color faithfully; avoid heavy filters/makeup on the area
Recent Advances

Recent Advances

  • Biologics: Transformative outcomes in psoriasis & hidradenitis suppurativa
  • Teledermatology: Access expansion for rural/underserved populations
  • AI in Dermatology: Decision support & melanoma screening assistance
  • Gene & Stem-cell Therapies: Emerging options for rare genetic skin disease